Pulmonary Physiology: Acid/Base and Compliance

When you take a large breath, it takes more pressure to inhale to a specific volume (peak pressure) than it does to hold the lungs at that volume (plateau pressure). Which of these is NOT a component of peak pressure? (L27, slide 23)

Which chemoreceptor determines the respiratory rate in a normal person? (L26, slide 15)

What is the effect on the specific compliance of the respiratory system after a pneumonectomy? (L27, Slide 20)

True or False: Compliance is defined as the change in volume of a system divided by the change in pressure which caused the deformation. (L27, slide 4)

A blood gas lab does NOT report which value?

In a patient with compensatory metabolic alkalosis, which of the following could be possible lab results? (L26, smartboard)

In the movie "The Abyss", divers breath oxygenated liquids when scuba diving at extreme depths to avoid life threatening differences in partial pressure between the external environment and their lungs. How would you expect the compliance of the divers' lungs to compare to yours, sitting at your computer at sea level? (L27, slide 8)

Which of the following factors does NOT contribute to the determination of total lung capacity? (L27, slide 6)

Which of the following will NOT cause Peak Pressure to increase? (L27, slide 26)

True or False: The phrenic nerves act on the lungs to control respiration. (L26, slide 13)

At which point of the respiratory cycle is the respiratory system least elastic? (L27, slide 18)

What is the correct order for activation of respiratory chemoreceptors in a healthy person (first activated to last activated)? (L26, slide 14)
I: CO2
II: O2
III: pH
IV: HCO3

A patient's test results come back with a pH of 7.32, a PaCO2 of 30, and an HCO3 of 15. What would be your diagnosis? (L26, slide 9)

Which volume/capacity of the lung cycle would be INCREASED in a patient suffering with asthma? (L27, slide 4)

The primary disease in acid/base disorders is determined by the... (L26, slide 6, verbal)

An uncoupling of the lung and chest wall can be caused by:
(L27, slide 14, infer)

Which of the following is a TRUE statement? (L26, slide 2)

When expanding an lung to a particular volume, more pressure is required upon inflation than is generated upon deflation. This concept is known as hysteresis. What effect would a decline in type II pneumocytes have on hysteresis? (L27, slide 16)

Over the usual tidal volume, if the compliance of the lung is 200 ml/cm H2O and the compliance of the chest wall is 200 ml/cm H2O, what is the compliance of the respiratory system as a whole? (L27, slide 21)

The TLC of the respiratory system is determined by the ____ and the RV of the system is determined by the ____. (L27, slide 14)
I: Lung
II: Alveoli
III: Diaphram
IV: Chest wall

A patient suffering from pulmonary fibrosis would have lungs that are ____ elastic when compared to a healthy person. (L27, slide 5, verbal)

Which of the following WOULD affect plateau pressure? (L27, slide 27 & 28)

After a 25 year-career working as a building contractor, your new patient comes to you complaining of trouble breathing. In your H&P, you come to learn that he was often exposed to asbestos at work. After performing a lung-function test, you find that his pressure-volume curve is ______ compared to a normal respiratory system curve. (L27, slide 22)

A patient's labs come back with the following results: blood pH=7.4, PaCO2=25. What is your diagnosis? (L26, smartboard)
I: Primary respiratory acidosis
II: Primary respiratory alkalosis
III: Primary metabolic acidosis
IV: Primary metabolic alkalosis
V: Secondary metabolic acidosis
VI: Secondary metabolic alkalosis

True or False: The acidity of the blood is directly proportional to the concentration of bicarbonate in the blood. (L26, slide 2)

A patient comes in to the ER with a PaCO2 of 10. What would you expect their blood pH to be in a case of acute acid/base imbalance? (L26, slide 3)

After performing an amniocentesis for a high-risk pregnancy at 25 weeks, you're lab results report a lecithin:sphingomyelin ratio of 1:1. Based on these results alone, what should you worry about if you have to deliver the baby tomorrow? (L27, slide 9-10)

In a spontaneously breathing patient, the static pressure on the lungs is determined by measuring the difference between the alveolar pressure and the pleural pressure. (L27, slide 12)

Which neural structure are NOT associated with unconscious control of breathing? (L26, slide 13)

Which of the following is ALWAYS true?
I: A fall in HCO3 is caused by primary metabolic acidosis
II: Hyperventilation leads to a fall in PCO2
III: A pH of 7.2 is indicative of acidemia
IV: Metabolic alkalosis is compensated by respiratory acidosis
(L26, all)