Renal 2: Filtration, Transport, and PSW1

1.

1 point

"Splay" is the difference between the amounts...
I: Filtered
II: Reabsorbed
III: Excreted
IV: Secreted

II, III

II, IV

I, III

IV, III

I, II

2.

1 point

Secretion primarily occurs in...

S3 of PCT

S1 of PCT

Collecting duct

Collecting tubule

S2 of PCT

3.

1 point

Which of the following free substances would not be found in Bowman's space at the same concentration as in plasma?

potassium

bicarbonate

threonine

albumin

sodium

4.

1 point

True or False: Sympathetic nervous activity can decrease GFR by causing podocyte contraction, decreasing the permeability of the nephron to water.

True

False

5.

1 point

Which area of the nephron reabsorbs the highest proportion of potassium?

Collecting duct

Distal Tuble

Thick ascending limb of Loop of Henle

Proximal tubule

6.

1 point

A tumor in the efferent arteriole of of the renal corpuscle would have what affect on GFR and RPF?

Decrease RPF

Decrease GFR

Increase RPF

No change in RPF

No change in GFR

Increase GFR

7.

1 point

Which of the following would cause stimulation of macula densa cells in the distal tubule?

Diabetes

High-salt diet

Exercise-induced hyponatremia

Liver failure

Congestive heart failure

8.

1 point

What is the GFR (in mL/min) of a patient with the following lab values?
Urine inulin concentration:3000 mg%
Plasma inulin concentration: 600 mg/L
Urine flow rate: 5.76 L/day

200 ml/min

288 ml/min

20 ml/min

2880 ml/min

28.8 ml/min

9.

1 point

The transport maximum is directly associated with which renal rate(s)?

Reabsorption rate

Secretion rate

Filtration rate

Excretion rate

10.

1 point

Liver failure would cause a decrease in GFR by which of the primary mechanisms?

decreased medullary blood flow

increased glomerular-capillary hydrostatic pressure

none of these

decreased osmotic capillary pressure

decreased glomerular-capillary hydrostatic pressure

increased osmotic capillary pressure

11.

1 point

Which area of the proximal convoluted tubule has the deepest microvillus brush border?

Impossible to tell

S3

S1

S2

12.

1 point

Which of the following molecules would have the smallest GFR?

H3CO3+

they are are filtered at the approximately the rate

HCO3-

H2CO3

13.

1 point

Which of the following substances is reabsorbed through primarily paracellular means in the proximal convoluted tubule?

Cl-

Sodium

Amino acids

Bicarbonate

All of these are absorbed paracellularly

Glucose

14.

1 point

What is the plasma concentration of PAH in a patient with the following lab results:
urine inulin concentration:1000 mg%
urine PAH concentration: 1000 mg%
plasma inulin concentration:20 mg/100ml
urine flow rate: 4 ml/min
Filtration Fraction: 10%

Can't tell from the data given

20 mg%

1 mg%

10 mg%

200 mg/100ml

2 mg/100ml

15.

1 point

In passing from the afferent areteriole to Bowman's space, place the layers you cross in the correct order:
I: Lamina rara externa
II: fenestra
III: Diaphragm
IV: Lamina densa
V: Lamina rara interna

I, IV, V, II, III

II, V, IV, I, III

V, IV, I, III, II

II, I, V, IV, III

I, IV, V, III, II

16.

1 point

Which of the following is NOT a requirement of a substance that can be used as a GFR marker?

Not metabolized or produced by the body

Not reabsorbed or secreted by the nephron

Does not alter GFR

Freely filtered at the glomerulus

Less than 70,000 Daltons

17.

1 point

Which of the following is not a barrier to renal filtration?

slit diaphrams between podocyte foot processes

glomerular-capillary epithelium

basement membrane

lamina rara externa