Coagulation

The following laboratory data were obtained from a 27 year old man with a long history of abnormal bleeding:

PT: normal
APTT: markedly prolonged
Factor VIII Coagulant activity: markedly decreased
Factor VIII related antigen: normal
Platelet Count: normal
Bleeding Time: normal

Which of the following disorders does this man most likely have:

The prothrombin time test requires that the patient's citrated plasma be combined with:

Thrombocytopenia is a characteristic of:

ADAMTS13 deficiency is responsible for thrombocytopenia found in:

Which of the following platelet responses is most likely associated with the classic von Willebrand disease?

A platelet count done by phase microscopy is 200 (reference range 150-450). A standardized template bleeding time on the same person is 15 minutes (reference range 4.5 +/- 1.5 minutes). This indicates that:

Coagulation vactors affected by warfarin (Coumadin) drugs are:

A 53 year old man was in recovery following a triple bypass operation. Oozing was noted from his surgical wound. The following laboratory data were obtained:

Hgb: 12.5 g/dL
Hct: 37%
PT: 12.3 secs
APTT: 34 secs
Platelet count: 40
Fibrinogen: 250 mg/dL

The most likely cause of bleeding would be:

Accute disseminate intravascular coagulation is characterized by:

To distinguish between hemophilia and von Willebrand disease, a patient with von Willebrand will present with which of the following test results?

Results APTT Platelet screen Ristocetin cofactor

result A abnormal normal normal
result B normal abnormal normal
result C abnormal abnormal abnormal
result D normal normal abnormal