K - Drive July CM1

1.

28. Cardiac remodelling is a de-compensatory mechanism following myocardium damage. The statement is ------

True

False

2.

13. The Tagline for Olmighty is ----------

Best deal on price & BP control

Best deal on BP control

Best deal on Price & only Price

Best deal on price control

3.

25. In mild to moderate renal & liver disorder HT patients on Concor -----

No dosage adjustment is required

Maximum dosage adjustment is required

None

Dosage adjustment is required

4.

14. Olmesartan exhibits --------- fold greater affinity towards AT1 than for AT2 receptors -------

> = 12,500

= 500

= 10000

< 12,500

5.

2. Currently, We have --------------- Campaign for Carbophage SR

Carbophage Tolerance

Carbophage Safety

Carbophage Top Brand

Carbophage Confidence Challenge

6.

9. The advantage of Metformin SR formulation include ----

Convenience

Compliance

OD administration

All of above

7.

17. Compared to Losartan, Olmesartan demonstrates highest pressor inhibition of ------- and thereby ensures BP control even during the early morning hours.

74% vs 25-40%

50% vs 65%

78% vs 355

77% to 50%

8.

16. Olmesartan is contraindicated in -------

Pregnant and lactating patients

Bilateral renal artery stenosis

Hypersensitivity reactions

All of the above

9.

29. --------- & ------- help distinguish among drugs, irrespective of age.

Size & Price

Shapes & Colours

Solid & Liquid

None

10.

10. As per UKPDS Metformin is associated with -------

Mortality reduction in diabetics

Reduction in diabetic complications

Reduction in CV complications in diabetes

All of above

11.

23. Primary objective of CIBIS II was to assess the effect of Bisoprolol on the -------

All cause mortality in HF patients

Sudden death reduction

Morbidity reduction

none of the above

12.

12. Each tablet of Olmighty 20 H cost -------

Rs 3.20

Rs 3.50

Rs 3.90

Rs 4.20

13.

7. Metformin acts by ------

Inhibiting AMP

Activating AMPK

Inhibiting insulin

Releasing Insulin

14.

24. CIBIS III study established that even beta blockers can be started earlier than ACEI in the management of HF therapy. Statement is -------

True

False

15.

5. Not all your patients have experienced the benefit of the --------- dose of Metformin due to gastric discomfort.

1 gram

500 mg

3 grams

2 grams

16.

20. Sympathetic over activation increases ----- of resistance vessels through adrenergic stimulation resulting in increased BP

Vasodilation

Vasoconstriction

Both the above

None of the above

17.

3. In Carbophage Confidence Challenge, one has to give a month’s samples of Carbophage to ----------

To Drs who report GI discomfort in patients with other brands

Convert Drs from other brands

Patients who Drs prescribe Carbophage

To Drs who require for personal use only

18.

22Agents which decrease conduction velocity of cardiac muscles is scientifically called as ----- drugs

Negative inotropic

Negative Arrhythmic

Negative chronotropic

Negative dromotropy

19.

26. Higher level of Noradrenalin can lead to ----

Mycordial damage

arrhythmias

Vasoconstriction

All the above

20.

21Patients of Heart Failure with marked limitation of Physical activity, Less than ordinary activity causes symptoms and Asymptomatic at rest comes under NYHA class -----

III

IV

I

II

21.

15. Compared to Telmisartan, Olmesartan demonstrates highest Pressor Inhibition of ------- and thereby ensures BP control even during the early morning hours.

55% vs 40%

74% vs 40%

45% vs 305

100% vs 75%

22.

30. The distinct heart – shaped tablets and different colours of all doses of Concor COR ensure ----

easy identification

improve adherence to therapy

improves survival benefits as compared to carvedilol brands which can be mistaken for other medications

All of the above

23.

27. Systolic HF is characterized by

Increase heart rate

Reduced CO

Decrease LVEF

All the above

24.

8. Metformin is excreted by ---------

All of above

Brain

Liver

Kidney

25.

1. Abbott”s brand of Metformin is

Metlong

Metaday

Melmet

Obimet

26.

6. The contraindication of Metformin include ---

Renal failure

Heat failure

Lactic acidosis

All of above

27.

18. Chronic SNS stimulation is associated with HF via a number of responses including ----

Tachycardia - decreased cardiac blood flow

Activation of the RAAS

Mycordial remodelling

All of the above

28.

19. Norepinephrine stimulates B1- adrenergic receptors in the heart to increase calcium influx and uptake, which enhances ------

myocardial contractility

myocardial perfusion

myocardial rhythm

myocardial conduction

29.

11. The half life of Metformin is --------

Up to 6 hours

Up to 3 hours

Up to 24 hours

Up to 12 hours

30.

4. Metformin release pattern of Carbophage is called as ------

Dual matrix polymer technology

Dual maximum polymer technology

Dual Metformin Polymer technology

Dual minimum poly technology