Exam 1 (Part 1)

1.

1 point

Which of the following is the description of Chenodeoxycholic acid?

Two OH groups present on cholic acid at 3 & 12

Two OH groups present on cholic acid at 9 & 12

Two OH groups present on cholic acid at 3 & 7

Two OH groups present on cholic acid at 7 & 12

2.

1 point

Which of the following is the most common Glycosaminoglycan found in cartilage?

Heparin

Hyaluronic acid

Keratin sulfate I

Chondroitin sulfate

3.

1 point

In the biosynthesis of Vitamin D which of the following is formed in the kidney?

7-Dehydrocholesterol

Cholecalciferol

25-Hydroxycalciferol

Calcitriol

4.

1 point

Which of the following disaccharides are classified as Reducing sugars?

Trehalose

Sucrose

Maltose

None of these

5.

1 point

Glycemic index refers to which of the following?

Measure of digestibility of starchy food and results in no change in glucose concentration

Measure of digestibility of starchy food and results in increase in glucose concentration

Measure of digestibility of starchy food and results in decrease in glucose concentration

None of these

6.

1 point

Nervous tissues have the highest concentration of which of the following?

Glycerophospholipids

Glycolipids

Gangliosides

None of these

7.

1 point

Which of the following is the major lipid of mitochondrial membranes?

Plasmalogen

Cardiolipin

Lecithin

Lysolecithin

8.

1 point

Which of the following is considered as a Mineralocorticoid?

Cortisol

Cortisone

Estradiol

Aldosterone

9.

1 point

Which of the following combinations of monosaccharides represent Trehalose?

C1 of glucose + C2 of Glucose

C1 of glucose + C1 of Glucose

C1 of glucose + C4 of Glucose

C1 of glucose + C1 of Galactose

C1 of glucose + C1 of Mannose

10.

1 point

Ethanolamine can be derived by decarboxylation of which of the following amino acids?

Cysteine

Methionine

Serine

Histidine

11.

1 point

GM3 is which one of the following?

Ceramide + GlNAc + Gal + (NANA)

Ceramide + Gal + Glc + (NANA)

Ceramide + GalNAc + Gal + (NANA)

Ceramide + Glc + Gal + (NANA)

12.

1 point

Which of the following intermediates is used for they synthesis of several adrenal steroid hormones?

Testosterone

Estradiol

Androsterone

Progesterone

13.

1 point

Aldonic acid is formed by which of the following reaction?

Oxidation of the aldehyde group

Reduction of the aldehyde group

Oxidation of the 6th CH2OH group

None of these

14.

1 point

Which of the following eicosanoid is responsible for inflammation in the lungs?

PGD2

PGE2

TXA2

LTA4

15.

1 point

Mucoprotein is also known as

Glycosaminoglycan

Proteoglycan

Glycoprotein

mucopolysaccharide

16.

1 point

Type A blood cell type is a tetrasaccharide that has which of the following monosaccharide in addition to the common trisaccharide in Type A, B and O?

N-Acetylgalactosamine

Galactose

Galactosamine

None of these

17.

1 point

PAF (Platelet aggregation factor) contains a saturated ether on C#1 and an _______ group on C#2. which of the following groups is present at C#2 of PAF?

Acyl

Formyl

Acetyl

None of these

18.

1 point

A proteoglycan belongs to which category of molecules?

Glycosaminoglycans

Glycoproteins

19.

1 point

Which of the following increases platelet aggregation?

PGD2

TXA4

LTA4

PGE2

20.

1 point

Phosphatidic acid is which one of the following descriptions?

Glycerol + 3 Fatty acids

Glycerol + 2 Fatty acids + Phosphate + alcohol

Glycerol + 2 Fatty acids + Phosphate

None of these

21.

1 point

The intermediate in the hydrolysis of starch is called?

Glycogen

Mucogen

Dextrin

Inulin

22.

1 point

Which of the following increases cAMP production in platelets, thyroid and lungs?

Leukotrienes

Thromboxanes

Prostacyclins

Prostanoid

23.

1 point

Which of the following eicosanoid is responsible for platelet inhibition?

PGD2

PGF2alpha

LTA4

PGI2

24.

1 point

Group III (group 3) prostanoids are made from which of the following unsaturated fatty acids?

Eicosapentaenoate

Docasahexenoate

Oleate

None of these

25.

1 point

Which of the following has between 12-14 glucopyranose units in one polysaccharide chain?

Starch

Glycogen

Cellulose

None of these

26.

1 point

Which of the following sugars is commonly found in human glycoproteins?

IdUA

GlcUA

GLcN

Gal

27.

1 point

Which of the following glycosidic bond is present in Maltose?

Alpha 1,2 glycosidic bond

Beta 1,2 glycosidic bond

Alpha 1,1 glycosidic bond

None of these

28.

1 point

Heparin is found most commonly in which of the following?

Mast cells

Cornea

Synovial fluid

Cartilage

29.

1 point

Which of the following contains an unsaturated ether at the number 1 carbon?

Cardiolipin

Plasmalogen

Phosphatidylcholine

Phosphatidylinositol

30.

1 point

Hyaluronic acid is an example of which of the following?

Glycosaminoglycan

Glycoprotein

31.

1 point

Hydrolysis of lactose will produce which combination of sugars?

Glucose + Fructose

Galactose + Glucose

Mannose + Galactose

None of these

32.

1 point

Galactosyceramide is a major glycosphingolipid in the brain. It contains a fatty acid called cerebronic acid. How many carbons are present in cerebronic acid?

20

22

24

18

33.

1 point

Which of the following description represents Lysolecithin?

Deacetylated C2 of (or from) Phosphatidylserine

Deacetylated C2 of (or from) PhosphatidylCholine

Deacetylated C2 of (or from) Phosphatidylethanolamine

None of these

34.

1 point

Sialic acids are not constituents of which of the following?

Glycoproteins

Ganglioside

Glycosaminoglycans

None of these

35.

1 point

In biosynthesis of Vitamin D, which of the following intermeidate is formed in the skin under UV light?

7-Dehydrocholesterol

25-Hydroxycholesterol

Cholecalciferol

Calcitriol

36.

1 point

Which of the following GAG molecules contain only the carboxylate group?

Heparin

Chondroitin 4-sulfate

Chondroitin 6-sulfate

Hyaluronic acid

Chitin

37.

1 point

Which of the following GAG is found to have a wide distribution?

Hyaluronic acid

Dermatan sulfate

Keratin Sulfate II

Heparin

38.

1 point

Which of the following is the correct way to represent Docasahexenoic acid?

C18:6 (4,7,10,13,16,19)

C18:6 (5,8,11,14,17,20)

C22:6 (4,7,10,13,16,19)

C22:6 (5,8,11,14,17,20)

39.

1 point

Which of the following can describe a sulfatide?

Sulfoglucosylceramide

Sulfogalactosylceramide

Sialoceramide

None of these

40.

1 point

Sphingomyelin can be described by which of the following

Ceramide + Phosphate + Serine

Ceramide + Phosphate + Choline

Ceramide + Phosphate + Inositol

Ceramide + Phosphate + Ethanolamine

41.

1 point

N or O-acyl derivatives of neuraminic acid are classified as?

Sialic acid

Salicylic acid

Glycoprotein

Glycoaminoglycans

42.

1 point

Keratin sulfate I is most commonly found in which of the following?

Synovial fluid

Cartilage

Cornea

Mast cells

43.

1 point

In the conversion from Leukotriene C4 (LTC4) to LTD4, which of the following amino acid is lost?

Glycine

Glutathione

Glutamic acid

Serine

44.

1 point

Gluconate is which of the following?

Aldonic acid

Alditol

Uronic acid

None of these

45.

1 point

Lactose contains which of the following combination of monosaccharides?

Galactose + Mannose

Glucose + Fructose

Glucose + Ribose

Galactose + Glucose

None of these

46.

1 point

Cortisol is classified as a _______

Mineralocorticoid

Glucocorticoid

Androgen

47.

1 point

Glucitol is formed by which of the following reactions?

Oxidation of the aldehyde group

Reduction of the aldehyde group

Oxidation of the 6th CH2OH group

None of these

48.

1 point

GPI (Glycosylphosphatidylinositol) is classified as which of the following?

Proteoglycan

Glycoprotein

Polysaccharide

Phosphatidic acid

49.

1 point

If the 6th carbon of Glucose gets oxidized, it is classified as which of the following?

Aldonic acid

Uronic acid

Alditol

None of these

50.

1 point

Which of the following eicosanoid is responsible for uterine contraction?

PGF2alpha

PGE2

PGD2

TXA2