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Anti-Migraine 5-HT1B/D

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1.
1 point
Which triptan is metabolized primarily by CYP3A4?
2.
1 point
Which was the first triptan on the market?
3.
1 point
Which triptan is metabolized both by MAO-A and CYP3A4?
4.
1 point
Which was the second triptan on the market?
5.
1 point
Which triptan is a substrate for P-gp efflux pumps?
6.
1 point
The metabolite of which triptan is eliminated in the feces?
7.
1 point
Which two triptans are metabolized by CYP1A2?
8.
1 point
Which triptan is metabolized by multiple CYP450s and has no active metabolite?
9.
1 point
Which triptan has the highest oral bioavailability?
10.
1 point
Which triptan has the lowest oral bioavailability?
11.
1 point
Which triptan is mainly metabolized by MAO-A and partly by CYP2D6?
12.
1 point
Which triptan has the highest affinity for 5-HT1B/D receptors?
13.
1 point
Which triptan has the longest half-life?
14.
1 point
Which triptan has the highest affinity for 5-HT1B receptors?
15.
1 point
The dose of which triptan must be reduced if the patient is taking Propranolol?
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