Immunology exam 1

A patient has arrived who is suffering from an unknown species of enteric helminth similar to tape worm. A minor case of edema has swelled around the site of the parasite, and a fluid sample was taken from the region. What should be expected if there has been a normal immune response (phylaxis) to the parasite?

pg. 33

What makes macrophages different from monocytes?

lecture 4 slide 5

The basic goal of the immune system is defense against infections microorganisms, BUT also _____ to self.

Which of the following is true regarding T lymphocytes?

page 40 of the text book

Which of the following describes a T cell that could be present in a thymus capsule?


lecture 6

Which of the following is false regarding the spleen?

Which of these proteins is not contained within neutrophils?



Table 2-2 of Kuby Immunology.

What is the name of macrophages in the kidney?



lecture 4 slide 6

Which type of stem cells can give rise to most, but not all, cell types?



lecture 3 slide 23

Which of the following is NOT a Reactive Oxygen Species utilized by some cells of the immune system to clear the body of pathogens?

Which of the following makes up the majority of circulating leukocytes?


lecture 4 slide 2

Which of the following are NOT derived from a myeloid progenitor cell?



Page 28

Which of the following are ways in which activated macrophages are more effective than resting macrophages in eliminating pathogens?

I. Increased phagocytic ability

II. Increased ability to kill ingested microbes

III. Decreased inflammatory mediator secretion

IV. Increased MHCII levels

Which statement best describes Ehrlich's Side Chain Theory?

Which transcription factor has only one purpose, to cause a hematopoetic stem cell to differentiate into a lymphoid cell?

Smallpox is a disease that is fatal in about what percentage of cases?

The work of Louis Pasteur did not lead to which of the following successful immunizations:

Pgs. 2-3

The first antibody produced in the (primary) response to an antigen is:

Tr1 T-reg cells culture CD4+ T cells in the presence of

I. IL5
II. antigen
III. IL10
IV. TGF-Beta and
V. IFN-Gamma

Which of the following is true about IgM?

Which of the following cells DOES NOT perform phagocytosis?


(lecture 4 slide 13)

Which of the following statements is true?

Where do T cells mature?

Which white blood cells can phagocytose pathogen?

lecture 4

Which of the following cells does not contain MHC 1?

A natural killer cell (NK) recognizes that there is a lack of MHC class I on a particular epithelial cell located in the GI tract. What event would most likely ensue after this physical contact?

Which of the answer options correctly pairs the binding of an MHC-peptide complex with its corresponding CD molecule during an intracellular infection?

What scientist was responsible for the discovery of dendritic cells and their involvement in the adaptive immunity?

Lecture 1 slide 30

How do Follicular Dendritic Cells differ from Dendritic cells?

CTL4A is a protein receptor that can exist on T cells. This receptor is known to regulate interaction between T cells and antigen presenting cells. What cluster of differentiations are directly affected by this protein receptor?

A patient goes to the doctor with a fever and his physician determines he has a viral infection. Which of the following played a pivotal role in the initial development of his fever?

lecture 2

Which of the following is NOT one of the signals required for T cell activation?

Which one of the following was NOT awarded the Nobel prize in 1980 for the major histocompatibility complex (MHC)?

lecture 1 slide 30

Which of the following is true about Follicular Dendritic Cells?

Which of the following effector T cell subsets regulate the response to extracellular pathogens?

Which type of antibody is responsible for allergic reactions?

When a naive B cell first encounters an antigen that matches its antibody, its progeny can differentiate into


lecture 5 slide 9

All of the following are granulocytes except:



lecture 4)

Which of the following is NOT true about basophils?



Table 2-2

Which of the following statements is false?

The main antibody produced in the (secondary) response to an antigen is:

Which type of cell from the myeloid lineage is most often associated with the development of allergies?

page 33

Which of the following is true?

How does lymph move throughout the lymphatic vessels?



slide 10 of lecture 6 or in chapter 2

Which of the following regions of soluble antibody is responsible for interacting with NK cells during antibody dependent cell-mediated cytotoxicity?

The largest lymphatic vessel, the _______ , empties into the subclavian vein and collects lymph from all of the body except the _______

lecture 6 slide 8

Different micro-niches within the bone marrow are thought to support specific stages of hematopoietic development. Which of the following statements is FALSE?

Our immune system quickly recognizes unique antigenic structures found on pathogens. These structures, that are not typically found in mammals, are called _____.

Chapter 1 (pg 14)

Which of the following cells inhibits apoptosis?


P.320 in 7th ed

Which of the following is NOT true of neutrophils?

p41-42