OKEP 28 Feb'14_Kirrus

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3) Among which of the following options, glycopeptides is used to compared with Linezolid for nosocomial pneumonia in the clinical study?

a) Teicoplanin

b) Vancomycin

c) Both

4) Which is the most reliable technique for the antibiotic activity in nosocomial pneumonia?

a) Epithelial lining Fluid

b) Lung tissue level

c) Blood serum level

5) This study evaluates hypothesis that linezolid is not superior to glycopeptides, i.e., vancomycin and teicoplanin, for the treatment of nosocomial pneumonia.

True

False

6) What are the outcomes evaluated for the trial?

a) Clinical cure

b) Side effect

c) Clinical cure, Eradication, Side effect

7) ________ Linezolid trials among drug comparison with vancomycin in _____ trial and teicoplanin in _____trial drug included_____ patients.

a) 9,2,7,2320

b) 8,6,2,2325

c) 9,7,2,2329

8) Analysis shows clinical cure relative risk and microbiological eradication relative risk was remarkably similar for the linezolid vs. glycopeptides.

True

False

9) One possibility for our hypothesis is not proven to be true because there drug concentrations of linezolid, measured by current ELF technology should not be assumed to correlate with clinical or microbiological outcomes.

True

False

10.

10) The Relative Risk (RR, Q, I2, 95% confidence interval) for the thrombocytopenia and gastrointestinal events are same in the linezolid compared with glycopeptides.

True

False

11.

11) Linezolid is associated with more renal dysfunction than teicoplanin and vancomycin.

True

False

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