therapeutics exam 5

Dracula has a viral load of 2500 U/mL. Which medications would be preferred for the treatment of his chronic hepatitis B?

You later find out that Dracula's chronic hepatitis B infection has resulted in decompensated cirrhosis. What combo medication would be appropriate for treatment?

Which of the oral HBV drugs has the greatest prevalence of resistance?

Unfortunately, Van Helsing pricked his finger with the same dagger used to kill hepatitis B positive Dracula. Van Helsing was started on Lamivudine, but resistance developed. What two medications could be used for Lamivudine resistant HBV?

Which HCV genotype is most common in the United States and the most difficult to treat?

If HCV is detected, the appearance of the HCV RNA virus occurs one month after exposure. Approximately 2 months later, ALT levels increase due to immune system creating antibodies and destroying hepatocytes. After how many months do the ALT levels return to normal, making it impossible to catch the detection phase?

Your patient is diagnosed with HCV. What is the next step?

If a HCV G1 patient is not eligible for interferon treatment, what 3 oral combo medications should be used as an alternative?

Which drug combo is recommended for HCV G2 treatment?

Which HCV genotype cannot use Peginterferons for treatment?

Which medication is indicated for HCV/HIV co-infection?

Which drug combo is recommended for decompensated cirrhosis due to HCV infection?

Which enzymes secreted from the pancreas are proteolytic?

Which toxins are related to acute pancreatitis?

Which infections are related to acute pancreatitis?
select 5

Which lab abnormalities would you see with acute pancreatitis?

Which of the following drugs are commonly associated with acute pancreatitis?
Select 5

Select common signs and symptoms of acute pancreatitis.

Which of the following pancreatic enzymes persists longer and is more specific to pancreatitis?

Which of the following tests is the gold standard for diagnosing acute pancreatitis?

The patient is found to have gallstone pancreatitis. Which procedure would be the best to relieve the obstruction?

Considering the Ranson's Criteria for AP, which of the following is an independent predictor of mortality?

Which opioid medications are best for management of pain in acute pancreatitis?
choose 2

Which of the following medications would inhibit pancreatic enzyme secretion and could possible be used for treatment of AP, even though it is controversial.

Which of the following could cause the development of chronic pancreatitis?

Which symptoms make up the classic triad for diagnosis of chronic pancreatitis?

Which of the following analgesics would be the first agents used to treat chronic pancreatitis?

Pancreatic enzyme supplements with the highest lipase content help to reduce steatorrhea.

Female patient presents with chronic lower abdominal pain, and diarrhea associated with stress altering serotonin levels. Which bowel condition is most likely present?

Patient appears malnourished with perianal fistulas, frequent bowel movements and increased CRP. The endoscopy shows a thickened intestinal lumen with a cobblestone appearance.
Which IBD does the patient have?

Sulfasalazine for IBD cannot be used in patients with sulfa allergies.

Which of the following Mesalamine agents for IBD allow daily dosing ?

Which medication for acute IBD exacerbations reaches all parts of the intestine?

Which of the following combo antibiotics would be useful in Crohn's disease especially when fistulas or abscess are present in the perineal area?

Which antibiotic may be useful in both Crohn's disease and ulcerative colitis?

Considering IBD therapy, corticosteroids are given parenteral, oral, or rectally for . . .

If your patient was started on IV methylprednisolone for severe flare up of IBD and there was no response after 5-7 days, which agent would you try next?

Which of the following immunosuppressants reserved for patients refractory to or dependent on steroids would be best for a fulminant active disease?

John is dependent on steroids and needs to be switched to an immunosuppressant with the most convenient dosing. Which agent would be best for John?

Biologic agents used for IBD are directed against TNF-alpha. Which agent would treat both crohn's disease and ulcerative colitis?

Which Biologic Agent used for IBD would be directed against alpha4 integrin, inhibiting leukocyte adhesion and migration?

Which supplement would be necessary for a patient taking sulfasalazine?