Pharm 1

A pt with a CAT score 8 and with 3 exacerbation/year is classified as what GOLD score?

In Phase 3 drug development what is being studied?

The use of ABX for COPD exacerbation is indicated in which of the followng situations?

In asthma there are a few thing we can do to possibly help before we Rx a med, such as have the pt change aspects of life. Many common things in life can cause an asthmatic rxn. Which of the following can cause a exacerbation of asthma?

A 7 y/o asthmatic pt comes in for a 3 month check up. The pt is on a medium dose ICS. Pt's mom makes sure he takes all his meds. He has needed to use his SABA on average 6/week. What should you do?

Certain people, 5-15%, can have an overlap allegice rxv with Cephalosporins. What other medication is associated with this overlap?

Pros: good against typical pathogens, low potential for drug interactions, cheap, peds ok, High dose > intermediate S. pneumoniae resistance
Cons: Allergy, Limited agaisnt PRSP, no effect vs atypical pathogens

a pt in group B of the GOLD classifications would be treated with what first choice medication/s

#1 goal in COPD

Pros: Good against both atypical and typical pathogens, peds OK, 1-2x/day dose
Cons: drug interactions, increasing resistence in S pneumoniae, GI intolerance, one kind doesnt work well on H Influenza

Corticosteroids are used in what type of pts with COPD

What percent of CAP is of unknown origin?

a high dose of an Fluticasone ICS is greater then ______ mcg/day divided 2x daily

Initial phase of TB drugs: _____ drugs/______ weeks; continuation pahse of TB drugs: _________ drugs/_____weeks

A beta agonistpulmonary medication, such as albuterol acts by what mechanism

Asthma is ________; COPD is ____________

Therapy a.k.a. drugs for Pertussis are these:

After use of an inhaler what should the pt always do

This is the "gold" standard of Rifamycins: ________. This is the Rifamycin used as a substitute for HIV patients whose antiretrovirals may have interactions: _______ (hint: see the email Brian sent you)

Pros: Good activity against typical and atypical respiratory pathogens; Excellent bio-availability; once daily dosing; short course therapy
Cons: emerging resistance to S pneumoniae; potential for collateral damage; safety concerns fro cardiac, peds and tendon ruptrues

A pt >12 y/o is considered to have persitient moderate asthma when meeting which of the following criterea? (sypmtoms; SABA use; lung function)

Treatment for Pneumonitis:

If a TB infection is labeled as MDR TB, what does that mean

Gold Standard for latent TB infections

These two types of drug delivery devices are good for any age, especially elderly of infants

What is the most common nebulizer adult dose of Albuterol?

What type of delivery system is appropriate for a 3 y/o with asthma?

This TB medication can have an adverse reaction of Peripheral Neuropathy:

in COPD serum concentrations of Theophylline should be at this level..

Levalbuterol is the mirror image to Albuterol chemically, that being said what is Levalbuterol's most common nebulizer dosage?

when is an antichlinergic agent typically used?

Due to overuse which one of these ABX's is no longer very effective if at all effective for an E. Coli infection?

Other Therapy: this drug/drug type is used sparingly due to concerns of worsening dyspnea

which asthma medication is shown to increase the risk of asthma related deaths when used alone?

When assessing a pt with suspected CAP they get a CURB 65 score of 2, what the heck does that mean?

after priming a MDI for the first time, shaking and preping the meds what are the next steps in usage?

Define pharmacokinetics:

Fomoterol and Salmeterol are

Pertussis: _________ wks similar to "coughing fits"; ________ wks similar to cold symptoms

Pros: low drug interactions, cheap, 2x/day dose, good vs typical and atypical
Cons: GI intolerance, allergy, contraindication for children, not for severe infections, can stain children's teeth

why is there a proper way to hold a DPI?

A TB pt comes to you complaining of Orange Urine, sweat and tears. You look over the list of the pts medications. The pt is (for the sake of this question) Rifampin, Ethambutol, Pyrazinamide and Isoniazid. Which of these medications is responsible for the Orange Urine

Mycoplasma pneumoniae, chlamydophia pneumoniae and Legionella pneumoniae are what type of pathogen?

This ethnicity has the highest rate of asthma

Corticosteroids are the most poeten anti-inflammatory agents for asthma treatment. Which is not one of their effects?

Signs and symptoms for pnuemonia include all of the following except:

Budesonide is a/n

Three things to consider in empiric choice of ABX's

A goal for treatment of asthma is

I realize we all hate lists and dumb questions like this but it is important to be able to identify the first line drugs for TB. One of the answers below labels a second line drug for TB. Because you are so familiar with the first line drugs for treatment of TB what is the one 2nd line drug?