OKEP 26 Dec'14

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Which of the following in not involved in the pathogenesis of Neuropathic pain?

a) Ectopic activity with spontaneous discharge in the peripheral nervous system

b) Hyperexcitability of the pain-signaling neurons

c) Sensitization of nociceptors by the local pricking and release of prostaglandins, bradykinin, serotonin, adenosine, and cytokines

d) Central sensitization at a dorsal horn level via the N-methyl-D-aspartate receptor

Which of the following part of nervous system involved in Neuropathic pain?

a) CNS

b) PNS

c) Both

d) None

Which of the following is involved in neurologic sensory dysfunction?
i. touch-evoked pain,
ii. intermittent abnormal sensations,
iii. spontaneous burning
iv. shooting pains
v. All of the above

a) i and ii

b) ii, iii and iv

c) iii and iv

d) i, ii, iii & iv

Dysesthesias is?

a) Normal perception of touch

b) Abnormal perception of a non-painful nature

c) Abnormal pain perception

d) Pain perception of noxious mechanical or thermal stimulus

Which of the following is used in topical treatment of Neuopathic pain?

a) gabapentin

b) lamotrigine

c) pregabalin

d) capsaicin

Hyperpathia is?

a) Delayed and explosive pain response to a noxious, or at times, non-noxious stimulus

b) Exaggerated pain responses to a mildly noxious mechanical or thermal stimulus

c) Painful response to an ordinarily non-noxious stimulus

d) Abnormal, intermittent but nonpainful sensations

10.

Which of the following is familial neuropathy?

a) Entrapment neuropathies

b) Trigeminal neuralgia

c) postherpetic neuralgia

d) Amyloid polyneuropathy

11.

___% Lidocaine Patch is approved by USFDA for the treatments for Neuropathic
Pain.

a) 1%

b) 2.5%

c) 5%

d) 10%

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