OKEP 23 Jan'15

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IMIREN is a potent broad spectrum bacteriostatic agent for intravenous administration.

True

False

What is the plasma half life of Cilastatin sodium?

a) 2 hour

b) 1.5 hour

c) 1 hour

IMIREN 500mg are infused over_________ and doses of IMIREN 1gm are infused over_________.

a) 20-30 min , 40-60min

b) 20-40 min, 1-2hour

c) 1-2 hour, 2-3 hour

Solutions of IMIREN I.V.range from colorless to yellow do not affect the potency of the product.

True

False

Can Imiren recommended for the pediatric patients with CNS infection?

Yes

What is the dosage of Imiren in severe and life threatening infection having moderately susceptible organisms strains of P.Aeruginosa?

a) 2gm

b) 4gm

c) 1.5gm

What is dosage of Imiren in hemodialysis patients having >70kg weight suffering the severe life threatening infection?

a) 250mg every 8 hour

b) 250mg every 12hour

c) 500mg every 12 hour

10.

Which enzyme is responsible for an inadequate antibacterial level of Imipenem?

a) Beta lactamases

b) Renal dehydropeptidase-I

c) Cephalosporinase

11.

What is the maximum dosage of IMIREN IV in adults and children?

a) Adults and children >40 kg: 4 g/day or 50 mg/kg. Children <40 kg: 3 g/day.

b) Adults and children >40 kg: 4 g/day or 50 mg/kg. Children <40 kg: 2 g/day.

c) Adults and children >40 kg: 5 g/day or 50 mg/kg. Children <40 kg: 2 g/day.

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