PHARM #1

1.

1 point

Once bound, a drug can give a new function to the target cell.

True

False

2.

1 point

The half-life of a particular drug is the amount of time that drug levels within the body decrease by 50%. Knowing the half-life of a drug is important for

Side Effects.

Route of Administration.

Safe Dosage Size.

Safe Dosage Intervals.

3.

1 point

To avoid drugs being excreted in the breast milk of a lactating mother, what can be done?
SELECT ALL THAT APPLY:

Dose immediately after breastfeeding.

Avoid drugs with a long half life.

Use the lowest effective dose for the shortest amount of time.

Avoid drugs with a short half life.

Dose immediately before breastfeeding.

Avoid Sustained release formulations.

4.

1 point

DIRECT interactions between drugs commonly occur where?

When combined in an IV solution

When contact occurs in the blood.

When mixed with gastric secretions.

In the liver.

5.

1 point

A single drug can have multiple trade names.

True

False

6.

1 point

In what ways can a drug cross a membrane?
SELECT ALL THAT APPLY

Passage Through Channels or Pores

Transport Systems

Special ID badge

They have to pay a toll

Direct Penetration

7.

1 point

Drug amounts below this plasma drug level produce no therapeutic response.

MEC

Trough Concentration.

Peak Concentration

Toxic concentration.

8.

1 point

All drugs act through receptors.

True

False

9.

1 point

What are the barriers to absorption with IV administration?

Capillary Wall.

Epithelial Cells.

There are no barriers.

Muscular Layer

10.

1 point

Q/T Interval Drugs are drugs that shorten the Q/T interval on the EKG, and could lead to life-threatening dysrhythmias.

True

False

11.

1 point

If a drug has a low therapeutic index, it is known that

This drug is relatively safe.

This drug is relatively unsafe.

This drug is not effective.

This drug is highly therapeutic.

12.

1 point

The placenta, similar to the BBB, constitutes an absolute barrier to certain molecules. This keeps the baby safe from drugs while in development.

True

False

13.

1 point

What is the primary use of a Placebo?

A control group within a clinical trial.

To support Obama.

An experimental group within a clinical trial.

If a patient is likely "faking" to obtain pain medication.

14.

1 point

The correct administration can ENSURE that the treatment will result in the therapeutic objective.

True

False

15.

1 point

What is teratogenesis?

The result of poly-pharmacy.

The formation of birth defects

A disease caused by drugs.

An uncommon drug response resulting from a genetic disposition.

16.

1 point

The nurse obtains an order that he knows is an unusually large dose for this patient. The nurse knows that his responsibility is to

Ask the patient about his/her usual dosage.

Cut the dose in half, and administer the medication to the patient.

Withhold the medication and contact the physician about the discrepancy.

Give the medication because the doctor is probably right.

17.

1 point

Determine whether this name is the Chemical, Generic, or Trade name:

Acetaminophen

Trade

Chemical

Generic

18.

1 point

During the Embryonic Period of development, it is likely that exposure to teratogens can produce what effects?

Decreased Functionality

Death

Superpowers

Gross Malformations

19.

1 point

Certain IV agents can cause serious local injury if the line becomes extravasated.

True

False

20.

1 point

Which pathological conditions can alter the drug responses?
SELECT ALL THAT APPLY

Altered Electrolyte Status

Kidney Disease

Liver Disease

Acid-Base Imbalances

21.

1 point

The detrimental interaction when Propranolol blocks the broncho-dialating effects of Albuterol, causing a reduction in therapeutic effects, is called a(n)

Physical Reaction

Synthesis Reaction

Inhibitory Reaction

Potentiative Reaction

22.

1 point

Antagonists have Intrinsic Activity.

True

False

23.

1 point

When monitoring for signs of liver injury after administering hepatotoxic drugs, the nurse should be aware of which signs?
SELECT ALL THAT APPLY:

Malaise

Dark Urine

Dark Colored stool

Light Colored Urine

Jaundice

Nausea

Light Colored Stool

Vomiting

24.

1 point

If a drug is said to have affinity, it is known that

The drug is going to cause an action once bound to its target receptor.

The drug is going to be attracted to its target receptor.

It is highly unstable, and free drug levels could rise.

The drug is going to be relatively therapeutic.

25.

1 point

No drug is a safe drug.

True

False

26.

1 point

What is the Grapefruit Juice Effect?

The decrease of blood levels of certain drugs because of the increase of metabolism.

The increase in blood levels of certain drugs because of the inhibition of metabolism.

The decreased absorption of drugs, caused by the acidic properties of the juice.

The decreased excretion of certain drugs, caused by the increase in bioavailability of certain drugs when mixed with Grapefruit Juice.

27.

1 point

A patient is having rare side effects that were later found to be caused by a genetic disposition that was previously unknown. This is called:

Idiosyncratic Effect

Iatrogenic Disease

Teratogenesis

Pharmacogenetics

28.

1 point

The strongest safety warning that a medication can have and still be on the market is known as the

Do Not Use list

Red Warning

Black Box Warning

BEERS list

29.

1 point

When a certain drug is said to be bioavailable, it means that

The drug is found plentiful in the environment.

The drug's effect is detrimental to many life systems.

The drug's benefits outweigh the risks.

The drug is able to reach systematic circulation from its site of administration.

30.

1 point

A patient that is on opioid analgesics presents with acute kidney failure. You know as a nurse that

The patient is going to have increased excretion of the drug.

That the dose must be raised to compensate for kidney pain.

Drug levels will be lowered in the body.

The patient could present with drug toxicities if the dose is not lowered or stopped completely.

31.

1 point

Endogenous Regulators, such as neurotransmitters and hormones, are agonists.

True

False

32.

1 point

Pediatrics cover all patients up to age ______

12

16

18

10

33.

1 point

Drugs can have more than one indication.

True

False

34.

1 point

If an antagonist has no intrinsic activity, how is it possible for it to produce an effect?

It prevents the binding of an agonist, therefore blocking the effects.

It does has intrinsic activity, and promotes a response.

It supports the binding of an agonist, thereby increasing the effectiveness of the response.

It prevents the binding of another antagonist, that can change the function of the cell.

36.

1 point

Only drugs that are _________, or have a transport system, can pass through the BBB.

Hydrophillic

Lipid Soluble

Lipophobic

Water Soluble

37.

1 point

A Drug that mimics the body's own regulatory molecules is called an_______
(DO NOT CAPITALIZE ANYTHING)

38.

1 point

The nurse is given an order to give a patient medication that the nurse knows is hepatotoxic. After assessing liver function and giving the meds, the nurse needs to check for liver damage by

Scheduling a CT scan.

Check for enzymes AST and ALT

Obtaining a urine sample.

Palpating for tenderness.

39.

1 point

The First Pass Effect, as often seen with Nitroglycerin taken orally, is

The capacity of the drug to completely bypass metabolism and enter circulation.

The capacity of the liver to completely inactivate a drug on its first pass through the liver.

The capacity of the kidneys to excrete the entire drug shortly after the first dose.

The capacity of the drug to cause Toxic responses on it's first dose.

40.

1 point

For pediatric patients, the calculation of drug dosing is based off of what principle?

Body Surface Area

Age

Shoe Size

Fat Percentage