OKEP Oct'15

1.

Name:

2.

Territory:

3.

Email Id:

4.

Renoque consists of Co-enzyme Q10 and this CoQ10 is also known as

(a) Ubiquinone

(b) Ubidecaquinone

(c) Ubidecarenone

(d) All of above

5.

From Which amino acid CoQ10 is mainly synthesized in the body?

(a) Valine

(b) Tyrosine

(c) Tryptophan

(d) Threonine

6.

A CoQ10 deficiency could result from________

(a) Impaired CoQ10 synthesis due to nutritional deficiencies (such as vitamin B6 deficiency)

(b) A genetic or acquired defect in CoQ10 synthesis or utilization

(c) Increased tissue needs resulting from a particular illness.

(d) All of the Above

7.

Which of the following statements is TRUE?

(a) CoQ10 functions as the unique protein component of the electron transport chain (ETC) not being attached to a protein itself.

(b) CoQ10 functions as the unique non-protein component of the electron transport chain (ETC) not being attached to a protein itself.

(c) CoQ10 functions as the unique protein component of the electron transport chain (ETC) attached to a protein itself.

(d) CoQ10 functions as the unique non-protein component of the electron transport chain (ETC)

8.

Indicative Usage of Renoque is__________

(a) Improvement of Renal function in Chronic Renal Failure

(b) Decreasing the need for dialysis

(c) Both (a) and (b)

(d) None

9.

RENOQUE is available as __________

(a) 160 mg Capsule for oral administration

(b) 180 mg Tablet for oral administration

(c) 180 mg Capsule for oral administration.

(d) 160 mg Tablet for oral administration

10.

Research articles have suggested that treatment with coenzyme Q10 (180 mg/ day) in patients with renal failure was associated with____________

(a) a significant reduction in blood urea and serum creatinine,

(b) Increase in creatinine clearance.

(c) Increase in urine output.

(d) All of the above

11.

Which deficiencies have been observed in patients with chronic renal failure?

(a) Antioxidant

(b) Vitamin

(c) Coenzyme Q10

(d) All

12.

Which of the following statements is FALSE about Co-enzyme Q10?

(a) It is benzoquinone compound synthesized naturally in the human body.

(b) This is water-soluble.

(c) The heart & kidneys contain the highest endogenous levels of Co-enzymes Q10 (compared to all other organs) because of high energy demand.

(d) CoQ10 is considered the central rate-limiting component of the MRC and each pair of electrons processed by the ETC must first interact with CoQ10.