Physiology 1

1.

1 point

Which of these is a characteristic of dynein?

Moves from + to -

Moves in the direction of the axon terminal to release NT

Is an important membrane protein

Needs cAMP for energy

Absence can lead to accumulation of glucocerebrosides

2.

1 point

What is present on a vesicle that signals it contains an substance that was taken into the cell by endocytosis?

Neurotransmitters

Ubiquitin tag

Phosphorylated carbohydrate

Clathrin

Spectrin

3.

1 point

What is the phospholipid bilayer composed of?

Hydrophobic head and hydrophilic tail

Amphipathic head and hydrophobic tail

Hydrophilic head and hydrophobic tail

Hydrophilic head and amphipathic tail

4.

1 point

How are integral proteins linked to membrane phospholipids?

Covalently

Ionic

Hydrogen bonds

Oligosaccharides

Disulfide bonds

5.

1 point

What is accumulated in cells in Tay Sachs Disease?

Fatty acids

Ganglioside GM2

Glucocerebrosides

Spectrin

Clathrin

6.

1 point

Which of these are true about peripheral proteins?

Have at most 7 domains

Are non covalently bonded to integral proteins

Helps form cytoskeleton

Composed of alpha helices of about 20 amino acids

Can be linked to fatty acids

7.

1 point

Which of these is NOT true about the phospholipid bilayer structure?

Cholesterol aids in stiffening membrane

Phospholipids cannot easily flip

Cholesterol can flip easily

Phospholipids cannot move at all

8.

1 point

Which of these is not a symptom of Gaucher Disease?

Bruising

Anemia

Bone problems

Swollen stomach

Muscle atrophy

9.

1 point

Which of these is NOT a characteristic of hereditary spherocytosis?

Red retinas

High reticulocyte count

Loss of RBC membrane

Extravascular hemolysis

Defective spectrin

10.

1 point

Which abnormal gene is responsible for Tay Sachs disease?

myc 8;14

p53

HEXA

BCL/ABL t (9;22)

TS t (4;15)

11.

1 point

Which disease includes malfunctioning macrophages?

Gaucher Disease

Tay Sachs Disease

HNPCC

Xeroderma Pigmentosum

Hereditary Spherocytosis

12.

1 point

How is the phospholipid bilayer oriented?

Polar head is oriented towards water while fatty acid tail is oriented away from water

Non polar head is oriented towards water while fatty acid tail is oriented away from water

Polar head is oriented away from water while fatty acid tail is oriented towards water

Polar head is oriented towards water while charged tail is oriented away from water