OKEP 02 September 2016

Is this your test? Login to manage it. If not, you can build an exam just like it.

This is a non-interactive preview of the quiz content.

Full Name:

Territory:

Email Id:

Lennox-Gastaut syndrome (LGS) is a severe childhood epilepy characterized by EEG with slow (---------) spike-and waves, several seizure types, and, typically, developmental delays and behavioral disturbances.

a) ≤5.2 Hz

b) ≤25 Hz

c) ≤52Hz

d) ≤2.5 Hz

The peak occurrence of LSG between---- years of age?

a) 3 and 8 years

b) 3 and 5 years

c) At 2 years

d) 5 and 10 years

Clobazam slightly different from classical benzodiazepine which confers less sedative properties in terms of negative adverse effects is ?

a) 1,5-benzodiazepines in that its oxygen

b) 1,4-benzodiazepines in that its nitrogen

c) 1,5-benzodiazepines in that its nitrogen

d) 1,4-benzodiazepines in that its oxygen

Mechanism of action is clobazam is similar to other benzodiazepines however Clobazam is believed to be?

a) a full agonist

b) a full antagonist

c) a partial antagonist

d) a partial agonist

Highest dose of clobazam used in OV-1012 phase III clinical trial is

a) 0.25mg/kg/day

b) 0.5mg/kg/day

c) 1.0 mg/kg/day

d) 1.5 mg/kg/day

Which of the following has dose has fewer seizure-related injuries in OV-1012 phase III clinical trial??

a) 0.25mg/kg/day

b) 0.5mg/kg/day

c) 1.0 mg/kg/day

d) 1.5 mg/kg/day

10.

Which of the following property of clobazam confer to less sedative effects than other benzodiazepines?

a) lower affinity for the GABAa subunits

b) greater selectivity for α2 subunits over α1 subunits

c) Both

d) None

11.

Total clobazam Market for July 2016 and growth is (INR Crs)?

a) 143.4& 3.5%

b) 151. & 5.3%

c) 84.5 & 5.6%

d) 89.2 & 8.3%

12.

Which of the following has negative growth?

a) FRISIUM

b) CLOBA

c) LOBAZAM

d) CLOZAM

Home Features Pricing FAQs Legal Sample Tests Build a Test Login/Sign Up